Saccharomyces boulardii: Antifungal Agents (Systemic, Oral) may diminish the therapeutic effect of Saccharomyces boulardii. Powder for suspension: Store under refrigeration at 2☌ to 8☌ (36☏ to 46☏). Tablet and suspension: Store at controlled room temperature of 15☌ to 25☌ (59☏ to 77☏).
Should be swished about the mouth and retained in the mouth for as long as possible (several minutes) before swallowing. Peritonitis (Peritoneal dialysis), prophylaxis for high risk situations (eg, during antibiotic therapy or PEG placement): Oral Suspension: Infants, Children, and Adolescents: 10,000 units/kg once daily (Warady 2012) Administration Infants: Oral: 200,000 to 400,000 units 4 times daily or 100,000 units to each side of mouth 4 times daily one study of 14 patients (neonates and infants) found higher cure rates using 400,000 units/dose 4 times daily (Hoppe 1997)Ĭhildren and Adolescents: Oral: 400,000 to 600,000 units 4 times daily administer half of dose to each side of mouth swish and retain in the mouth for as long as possible before swallowing. Note: Powder for compounding: 1/ 8 teaspoon (500,000 units) to equal approximately 1/ 2 cup of water give 4 times/day Dosing: Geriatric Intestinal infections: Oral tablets: 500,000-1,000,000 units every 8 hours Oral candidiasis: Suspension (swish and swallow): 400,000-600,000 units 4 times/day swish in the mouth and retain for as long as possible (several minutes) before swallowing Hypersensitivity to nystatin or any component of the formulation Dosage and Administration Dosing: Adult Treatment of susceptible cutaneous, mucocutaneous, and oral cavity fungal infections normally caused by the Candida species Contraindications Symptomatic relief from candidiasis: 24-72 hours Use: Labeled Indications Binds to sterols in fungal cell membrane, changing the cell wall permeability allowing for leakage of cellular contents Pharmacokinetics/Pharmacodynamics Absorptionįeces (as unchanged drug) Onset of Action
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